反応式
[CH3:1][C:2]([C@@H:4]1[CH2:9][CH:8]=[C:7]([CH2:10][OH:11])[CH2:6][CH2:5]1)=[CH2:3].CC(C1CC=C(C[O:22]C(C)=O)CC1)=C.CC1(C)C2CC1CCC12OC1>>[CH:7]1([CH2:10][OH:11])[CH2:6][CH:5]=[C:4]([C:2]([OH:22])([CH3:1])[CH3:3])[CH2:9][CH2:8]1参加物
実験手順
The applicant's first preferred method of preparing perillyl alcohol from pure beta pinene oxide is to react pure beta pinene oxide with anhydrous sodium acetate and glacial acetic acid to produce p-menth-1-en-8-acetoxy-7-ol (C), after which the p-menth-1-en-8-acetoxy-7-ol is pyrolyzed to perillyl alcohol in a yield of approximately fifty percent (50%). This represents a facile two step procedure using inexpensive, safe reagents. The applicant's second preferred method of producing perillyl acetate and perillyl alcohol from pure beta pinene oxide is to react pure beta pinene oxide with an acid resin to produce p-menthene-7,8-diol (D) that is then acetylated to afford 7-acetoxy-p-menth-1-en-8-ol (E) which is then dehydrated by any of five different procedures to yield perillyl acetate that can be hydrolyzed to perillyl alcohol.
出典と根拠
- ORDレコード
- ord-33519a9634d54f82945f0e0cd70a9489
- 出典データセット
- uspto-grants-1999_11
- 特許番号
- US05994598
関連ノート
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