HCID 21543532、化合物 → HCID 21442848、化合物
反応式
[N+:1]([C:4]1[CH:27]=[CH:26][CH:25]=[CH:24][C:5]=1[C:6]([O:8][CH2:9][CH2:10][N:11]1[CH2:16][CH2:15][N:14]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([Cl:23])[CH:18]=2)[CH2:13][CH2:12]1)=[O:7])([O-])=O>[Pd].CO>[C:6]([O:8][CH2:9][CH2:10][N:11]1[CH2:16][CH2:15][N:14]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([Cl:23])[CH:18]=2)[CH2:13][CH2:12]1)(=[O:7])[C:5]1[C:4](=[CH:27][CH:26]=[CH:25][CH:24]=1)[NH2:1]参加物
4
実験手順
5.75 G. (0.015 mol) of 2-(4-m-chlorophenyl-piperazino)-ethyl 2-nitrobenzoate in 100 ml. of methanol is hydrogenated at ambient temperature and at atmospheric pressure, in the presence of 1 g. of 10% palladium on charcoal. The theoretical amount of hydrogen (1 1.) is absorbed in 40 minutes. The catalyst is filtered off, the methanol is evaporated from the filtrate, and the residue is recrystallised from isopropyl alcohol to give 4 g. (yield = 74.1%) of 2-(4-m-chlorophenylpiperazino)-ethyl anthranilate, which melts at 77° and which was shown to be identical, using a mixed melting point, to the product of Examples 14 and 16.