4-Aminophenol → Phenolindophenol

HRID 1606693

反応式

HRID 1606693 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.N[C:10]1[CH:11]=[CH:12][C:13](C)=[C:14]([OH:16])[CH:15]=1>[OH-].[Na+]>[CH:7]1[C:2](=[N:1][C:11]2[CH:10]=[CH:15][C:14]([OH:16])=[CH:13][CH:12]=2)[CH:3]=[CH:4][C:5](=[O:8])[CH:6]=1

参加物

4

反応物 2

HCID 4034-AminophenolHCID 178185-Amino-2-methylphenol

生成物 1

HCID 10379Phenolindophenol収率 60.2%

試薬・触媒・溶媒 1

HCID 14798Sodium Hydroxide溶媒2 回

実験手順

0.01 mole (1.09 g) of paraaminophenol is dissolved in 100 cm3 of a 0.1 N NaOH solution. A second solution of 0.01 mole (1.23 g) of 5-amino-2-methyl phenol in 100 cm3 of a 0.1N NaOH solution is also prepared. The two solutions are then mixed and air is bubbled in the resulting mixture for about 5 hours at ambient temperature. The reaction medium is then acidified with sufficient HCl to pH 5 to produce 1.2 g of said indophenol which is then filtered off and which, after recrystallization from a dimethylformamide-water mixture, melts at 215°.

後処理

  1. additionThe two solutions are then mixed
  2. customair is bubbled in the resulting mixture for about 5 hours at ambient temperature

出典と根拠

ORDレコード
ord-c37537883b414163b57e733cf95dbcb6
出典データセット
uspto-grants-1976_04
特許番号
US03953508

関連ノート

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