Ethanolamine → 2-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

HRID 1606851ノート

反応式

HRID 1606851 の反応式
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4](Cl)[C:3]=1[N+:10]([O-:12])=[O:11].[CH2:13]([CH2:15][NH2:16])[OH:14]>>[OH:14][CH2:13][CH2:15][NH:16][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH:16][CH2:15][CH2:13][OH:14])[C:3]=1[N+:10]([O-:12])=[O:11]

参加物

3

反応物 2

HCID 700EthanolamineHCID 292282,4,6-Trichloronitrobenzene

生成物 1

HCID 200710912-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

実験手順

0.132 mole (30 g) of 2,4,6-trichloronitrobenzene were heated at 95° C. in 120 ml of ethanolamine. After 30 minutes the reaction medium was poured over 240 g of an ice-water mixture. The desired product precipitated out and was filtered, washed with water and then dried under vacuum in the presence of phosphorus pentoxide. After recrystallization from absolute ethanol, it melted at 154° C.

後処理

  1. customThe desired product precipitated out
  2. filtrationwas filtered
  3. washwashed with water
  4. dry with materialdried under vacuum in the presence of phosphorus pentoxide
  5. customAfter recrystallization from absolute ethanol, it melted at 154° C.

出典と根拠

ORDレコード
ord-03db87c1a2a64f06919127391a9822ca
出典データセット
uspto-grants-1989_09
特許番号
US04863482

反応ノート

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