2-Methoxyethylamine → 5-Chloro-N1-(2-methoxyethyl)-N3-methyl-2-nitro-1,3-benzenediamine

HRID 1606856ノート

反応式

HRID 1606856 の反応式
[CH3:1][NH:2][C:3]1[CH:8]=[C:7]([Cl:9])[CH:6]=[C:5](Cl)[C:4]=1[N+:11]([O-:13])=[O:12].[CH3:14][O:15][CH2:16][CH2:17][NH2:18]>>[CH3:1][NH:2][C:3]1[CH:8]=[C:7]([Cl:9])[CH:6]=[C:5]([NH:18][CH2:17][CH2:16][O:15][CH3:14])[C:4]=1[N+:11]([O-:13])=[O:12]

参加物

3

反応物 2

HCID 80182-MethoxyethylamineHCID 20071071HCID 20071071、化合物

生成物 1

HCID 198511585-Chloro-N1-(2-methoxyethyl)-N3-methyl-2-nitro-1,3-benzenediamine

実験手順

0.09 mole (20 g of 2-methylamino-4,6-dichloro nitrobenzene was added portionwise to 80 ml of 2-methoxyethyl amine preheated to 80° C. After 2 hours' heating, the reaction medium was diluted with 100 ml of ice water and the desired product precipitated out. After filtering, water washing then vacuum drying in the presence of P2O5, it was recrystallized from 96° ethanol. It melted at 93° C.

後処理

  1. custompreheated to 80° C
  2. temperatureAfter 2 hours' heating
  3. customthe desired product precipitated out
  4. filtrationAfter filtering
  5. dry with materialwater washing then vacuum drying in the presence of P2O5, it
  6. customwas recrystallized from 96° ethanol

出典と根拠

ORDレコード
ord-d3c264f613b54c85a60194c974e79929
出典データセット
uspto-grants-1989_09
特許番号
US04863482

反応ノート

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