Acetic Anhydride → 3-Methyl-4-acetoxybenzofuran
反応式
[CH3:1][C:2]1[C:6]2[C:7]([OH:11])=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][CH:3]=1.[C:12](OC(=O)C)(=[O:14])[CH3:13].C(N(CC)CC)C>O1CCCC1>[CH3:1][C:2]1[C:6]2[C:7]([O:11][C:12](=[O:14])[CH3:13])=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][CH:3]=1参加物
5
実験手順
A solution of 3-methyl-4-hydroxybenzofuran (5.0 gm, 34.7 mmoles), acetic anhydride (50 mL) and triethylamine (25 mL) in tetrahydrofuran (150 mL) was stirred at room temperature overnight. The volatiles were removed in vacuo and the residue was purified by chromatography on silica gel. Elution with 15% ethylacetate in hexane yielded 3-methyl-4-acetoxybenzofuran.
後処理
- customThe volatiles were removed in vacuo
- customthe residue was purified by chromatography on silica gel
- washElution with 15% ethylacetate in hexane
出典と根拠
- ORDレコード
- ord-69396100fb174d618f6d5b7d7400c5e1
- 出典データセット
- uspto-grants-1989_09
- 特許番号
- US04863958
反応ノート
読み込み中…