Ethyl benzylidenecyanoacetate → Ethyl 2-cyano-3-phenylpropanoate

HRID 1607388

反応式

HRID 1607388 の反応式
[CH2:1]([O:3][C:4](=[O:15])[C:5]([C:13]#[N:14])=[CH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2]>C1C=CC=CC=1.[Pd]>[CH2:1]([O:3][C:4](=[O:15])[CH:5]([C:13]#[N:14])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2]

参加物

4

反応物 1

HCID 74845Ethyl benzylidenecyanoacetate

生成物 1

HCID 228103Ethyl 2-cyano-3-phenylpropanoate収率 92.5%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 241Benzene溶媒

実験手順

A solution of 4.56 g of the ester obtained in 30 ml of benzene was hydrogenated over 0.45 g of a 10% palladium/charcoal under a hydrogen atmosphere at room temperature for 4 hours. After filtration of the catalyst, the reaction mixture was concentrated under reduced pressure to obtain 4.26 g of 2-cyano-3-phenylpropionic acid ethyl ester as a colorless oil.

後処理

  1. filtrationAfter filtration of the catalyst
  2. concentrationthe reaction mixture was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-c3f8c538c3994304819a7c2b309f2c97
出典データセット
uspto-grants-1989_09
特許番号
US04863904

関連ノート

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