3-Ethoxycarbonyl-4-(1-naphthyl)-3-butenoic acid → HCID 19790805、化合物

HRID 1607396ノート

反応式

HRID 1607396 の反応式
[CH2:1]([O:3][C:4]([C:6](=[CH:11][C:12]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH:15]=[CH:14][CH:13]=1)[CH2:7][C:8]([OH:10])=[O:9])=[O:5])[CH3:2]>C(O)(=O)C.[Pd]>[CH2:1]([O:3][C:4]([CH:6]([CH2:11][C:12]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH:15]=[CH:14][CH:13]=1)[CH2:7][C:8]([OH:10])=[O:9])=[O:5])[CH3:2]

参加物

4

反応物 1

HCID 540390073-Ethoxycarbonyl-4-(1-naphthyl)-3-butenoic acid

生成物 1

HCID 19790805HCID 19790805、化合物収率 72.5%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 176Acetic Acid溶媒

実験手順

A solution of 2.0 g of 3-ethoxycarbonyl-4-(1-naphthyl)-3-butenoic acid in 100 ml of acetic acid was hydrogenated over 900 mg of a 10% palladium/charcoal under a hydrogen atmosphere at room temperature. After filtration of the catalyst, the reaction solution was concentrated under reduced pressure to obtain 1.46 g of 3-ethoxycarbonyl-4-(1-naphthyl)butyric acid as a brown oil.

後処理

  1. filtrationAfter filtration of the catalyst
  2. concentrationthe reaction solution was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-68a634804a444144ab0ae14dee124d88
出典データセット
uspto-grants-1989_09
特許番号
US04863904

反応ノート

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