n-((4-Benzylmorpholin-2-yl)methyl)acetamide → N-(morpholin-2-ylmethyl)acetamide
反応式
[C:1]([NH:4][CH2:5][CH:6]1[O:11][CH2:10][CH2:9][N:8](CC2C=CC=CC=2)[CH2:7]1)(=[O:3])[CH3:2]>C(O)C.C(O)(=O)C.[Pd]>[C:1]([NH:4][CH2:5][CH:6]1[O:11][CH2:10][CH2:9][NH:8][CH2:7]1)(=[O:3])[CH3:2]参加物
5
実験手順
2-Acetylaminomethyl-4-benzylmorpholine (120 g) is dissolved in a mixture of ethanol (1000 ml) and acetic acid (30 ml) and hydrogenated over 10% palladium on carbon (5 g) at about 60° C. After the calculated amount of the hydrogen is absorbed, the catalyst is filtered off. The filtrate is evaporated under reduced pressure to give the title compound as an oil.
後処理
- customAfter the calculated amount of the hydrogen is absorbed
- filtrationthe catalyst is filtered off
- customThe filtrate is evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-aed908b8f1af456baaf178f72a08fb01
- 出典データセット
- uspto-grants-1989_09
- 特許番号
- US04870074
反応ノート
読み込み中…