反応式
Cl.Cl.[NH2:3][CH2:4][CH2:5][S:6][C:7]1[N:12]2[CH:13]=[CH:14][N:15]=[C:11]2[CH:10]=[CH:9][CH:8]=1>C(Cl)(Cl)Cl>[NH2:3][CH2:4][CH2:5][S:6][C:7]1[N:12]2[CH:13]=[CH:14][N:15]=[C:11]2[CH:10]=[CH:9][CH:8]=1参加物
3
実験手順
After a suspension of 5-[2(amino)ethylthio]imidazo-[1,2-a]pyridine dihydrochloride (13.31 g, 50 mmloes) in chloroform (200 ml) was washed with 3N sodium hydroxide (50 ml), the aqueous layer was extracted with chloroform, the combined chloroform layer was dried over anhydrous magnesium sulfate. Then, the solvent was distilled off to obtain 9.63 g of the desired product (99.7%, pale yellow oily product).
後処理
- washwas washed with 3N sodium hydroxide (50 ml)
- extractionthe aqueous layer was extracted with chloroform
- dry with materialthe combined chloroform layer was dried over anhydrous magnesium sulfate
- distillationThen, the solvent was distilled off
出典と根拠
- ORDレコード
- ord-74624a2a1b5b49229391bdcce7eb0e9a
- 出典データセット
- uspto-grants-1995_03
- 特許番号
- US05395839
関連ノート
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