Hydroxyamine hydrochloride → 4(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketoxime

反応式

[CH:1]1([C:8]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[CH:12][CH:11]=2)=O)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[NH2:29][OH:30]>>[CH:1]1([C:8]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[CH:12][CH:11]=2)=[N:29][OH:30])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

反応物 2

HCID 443297Hydroxyamine hydrochloride

HCID 200842384-(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketone

生成物 1

HCID 736588494(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketoxime

実験手順

In analogy to the procedure of Example IV, the title compound is prepared from 12.9 g (35.9 mmol) of the compound from Example XIII and 3.75 g (53.9 mmol) of hydroxylamine hydrochloride.

出典と根拠

ORDレコード: ord-969c54b0d519450ba2931e47bb37c656
出典データセット: uspto-grants-1995_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05399698

反応ノート

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