Sodium Iodide → Tert-butyl[(6-iodohexyl)oxy]dimethylsilane

HRID 1609454

反応式

HRID 1609454 の反応式
[I-:1].[Na+].[Si:3]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]Cl)([C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:5])[CH3:4]>CC(C)=O>[Si:3]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][I:1])([C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:5])[CH3:4]

参加物

4

反応物 2

HCID 5238Sodium IodideHCID 10083489[(6-Chlorohexyl)oxy](1,1-dimethylethyl)dimethylsilane

生成物 1

HCID 13972989Tert-butyl[(6-iodohexyl)oxy]dimethylsilane

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A solution of sodium iodide (13.5 g, 90 mmol) and 1-(tert-butyldimethylsilyloxy)-6-chloro-hexane (Preparation 20) (8.35 g, 22 mmol) in acetone (70 ml) was refluxed overnight. The reaction mixture was cooled to room temperature and filtered. The filtrate was worked-up (hexane) to give the desired compound as yellow oil.

後処理

  1. filtrationfiltered

出典と根拠

ORDレコード
ord-95e4696a421a497d915996c9261bd306
出典データセット
uspto-grants-1995_03
特許番号
US05401732

関連ノート

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