(2S)-2-[[4'-[[(1,1-dimethylethyl)amino]carbonyl]-3'-fluoro-5-(trifluoromethyl) [1,1'-biphenyl]-2-yl]oxy]-propanoic acid → (2S)-2-[[5-chloro-4'-[[(1,1-dimethylethyl)amino]carbonyl]-3'-fluoro[1,1'-biphenyl]-2-yl]oxy]-propanoic acid

HRID 16112

反応式

[CH3:1][C:2]([NH:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[C:18](C(F)(F)F)[CH:17]=[CH:16][C:15]=2[O:24][C@@H:25]([CH3:29])[C:26]([OH:28])=[O:27])=[CH:10][C:9]=1[F:30])=[O:7])([CH3:4])[CH3:3].B(C1C=C([Cl:46])C=CC=1O[C@@H](C)C(O)=O)(O)O>>[Cl:46][C:18]1[CH:17]=[CH:16][C:15]([O:24][C@@H:25]([CH3:29])[C:26]([OH:28])=[O:27])=[C:14]([C:11]2[CH:12]=[CH:13][C:8]([C:6]([NH:5][C:2]([CH3:4])([CH3:3])[CH3:1])=[O:7])=[C:9]([F:30])[CH:10]=2)[CH:19]=1