4-[2,6-Dichloro-4-(phenylmethoxy)phenoxy]butan-1-ol → 3,5-Dichloro-4-(4-hydroxybutoxy)phenol
反応式
[Cl:1][C:2]1[CH:13]=[C:12]([O:14]CC2C=CC=CC=2)[CH:11]=[C:10]([Cl:22])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9].[H][H]>[Pd]>[Cl:1][C:2]1[CH:13]=[C:12]([OH:14])[CH:11]=[C:10]([Cl:22])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9]参加物
4
実験手順
This compound was prepared in a manner analogous to that of Step A of this example, using 12.2 grams (0.036 mole) of 4-[2,6-dichloro-4-(phenylmethoxy)phenoxy]butan-1-ol and 0.5 gram (catalyst) of 10% palladium on carbon and a theoretical amount of hydrogen gas in a Parr Hydrogenator. The yield of the subject compound was 9.3 grams. The NMR spectrum was consistent with the proposed structure.
後処理
- customThis compound was prepared in a manner analogous to that of Step A of this example
出典と根拠
- ORDレコード
- ord-68940b919345426ba63d0c73b4754ffe
- 出典データセット
- uspto-grants-2006_01
- 特許番号
- US06987194B2
反応ノート
読み込み中…