Chlorobenzene → Benzoic Acid

HRID 1613962

反応式

HRID 1613962 の反応式
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1(P(C(C(P(C2C=CC=CC=2)C2C=CC=CC=2)C)C)C2C=CC=CC=2)C=CC=CC=1.[C:38](=O)([O-:40])[O-:39].[K+].[K+].[C]=O>[Pd](Cl)Cl.O>[C:38]([OH:40])(=[O:39])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

7

反応物 4

HCID 7964ChlorobenzeneHCID 11430Potassium CarbonateHCID 3882352ChiraphosHCID 178418416HCID 178418416、化合物2 回

生成物 1

HCID 243Benzoic Acid

試薬・触媒・溶媒 2

HCID 24290Palladium Chloride触媒HCID 962Water溶媒

反応条件

温度
210 °C

実験手順

In an autoclave made of metal were placed 11.2 g of chlorobenzene, 17.5 mg of palladium chloride, 427 mg of bisdiphenylphosphinobutane and 3.1 g of potassium carbonate. The air in the autoclave was replaced with carbon monoxide introduced thereinto in several times, after which carbon monoxide was further introduced to its pressure therein to 50 kg/cm2. The reaction was carried out with stirring for 3 hours on a salt bath at a bath temperature of 210° C. After completion of the reaction, the reaction mixture was cooled to room temperature and water was added. The aqueous layer was separated, after which acid was added thereto and the deposited crystals were collected by

後処理

  1. additionintroduced
  2. customAfter completion of the reaction
  3. temperaturethe reaction mixture was cooled to room temperature
  4. customThe aqueous layer was separated
  5. additionafter which acid was added
  6. customthe deposited crystals were collected by

出典と根拠

ORDレコード
ord-095b683e6d924901b542fa981debd102
出典データセット
uspto-grants-1993_03
特許番号
US05194631

関連ノート

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