Hydrochloric Acid → HCID 14037832、化合物
反応式
[CH3:1][C:2]1([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[NH:6]C(=O)N[C:3]1=[O:8].[OH-:17].[Na+].Cl>O>[CH3:1][C@@:2]([C:3]([OH:17])=[O:8])([CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[NH2:6]参加物
5
実験手順
54.6 g 5-methyl-5-phenethyl-hydantoin (0.25 Mol) are reacted with 30 g sodium hydroxide (0.75 Mol) and 150 ml water for 3.5 hours in an autoclave at an oil bath temperature of 180° C. After cooling, 350 ml H2O are added and the clear, light brown solution adjusted with hydrochloric acid to pH 7.0. The white precipitate is suctioned off, washed with 20 mg H2O and dried in a vacuum drying cabinet at 65° C. The produce is recrystallized twice from water.
後処理
- temperatureAfter cooling
- washwashed with 20 mg H2O
- customdried in a vacuum
- customdrying cabinet at 65° C
- customThe produce is recrystallized twice from water
出典と根拠
- ORDレコード
- ord-38b360bf92de4233afb148c329c1c645
- 出典データセット
- uspto-grants-1993_03
- 特許番号
- US05194644
反応ノート
読み込み中…