3,5-Dimethylpyrazole → 3,5-Dimethylpyrazole

HRID 1614102ノート

反応式

HRID 1614102 の反応式
[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[NH:4][N:3]=1.Br[CH2:9][CH2:10][Cl:11].BrCCBr>O1CCCC1>[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[N:4]([CH2:9][CH2:10][Cl:11])[N:3]=1.[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[NH:4][N:3]=1

参加物

6

反応物 3

HCID 62103,5-DimethylpyrazoleHCID 78391,2-DibromoethaneHCID 78491-Bromo-2-Chloroethane

生成物 2

HCID 62103,5-DimethylpyrazoleHCID 11499791-(2-chloroethyl)-3,5-dimethyl-1H-pyrazole

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

When an equivalent amount of 3,5-dimethylpyrazole is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19 using tetrahydrofuran as solvent, 2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl chloride is isolated after column chromatography (3,5-dimethylpyrazole, Aldrich, 24%, C).

出典と根拠

ORDレコード
ord-34f2e8ea8d294d83a3379b0780931942
出典データセット
uspto-grants-1993_03
特許番号
USRE034201

反応ノート

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