Dimethylformamide → HCID 86667820、化合物
反応式
[CH3:1][C:2]1[N:7]2[N:8]=[C:9]([CH:11]([CH3:16])[CH2:12][C:13](O)=[O:14])[N:10]=[C:6]2[C:5]([CH3:17])=[N:4][CH:3]=1.C(Cl)(=O)C([Cl:21])=O.CN(C=O)C>C(Cl)Cl>[CH3:1][C:2]1[N:7]2[N:8]=[C:9]([CH:11]([CH3:16])[CH2:12][C:13]([Cl:21])=[O:14])[N:10]=[C:6]2[C:5]([CH3:17])=[N:4][CH:3]=1参加物
5
実験手順
To a solution of 3-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)butanoic acid (200 mg, 0.086 mmol) in DCM (15 mL) was added oxalyl chloride (3 mL) and DMF (0.1 mL). The mixture was stirred at room temperature for 2 h. The mixture was then evaporated under reduced pressure to give the product as a brown solid (208 mg, 96% yield).
後処理
- customThe mixture was then evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-16c51014509141acaa07677d717f2074
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08765760B2
反応ノート
読み込み中…