Salicylaldehyde → 2-[(2,6-Dibromophenyl)iminomethyl]phenol
反応式
[Br:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([Br:9])[C:3]=1[NH2:4].[CH:10](=O)[C:11]1[C:12](=[CH:14][CH:15]=[CH:16][CH:17]=1)[OH:13].C(N(CC)CC)C>C1(C)C=CC=CC=1.C1(C)C=CC(S(O)(=O)=O)=CC=1>[Br:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([Br:9])[C:3]=1[N:4]=[CH:10][C:11]1[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=1[OH:13]参加物
6
実験手順
A solution of 2,6-dibromoaniline (9 g, 35.9 mmol), salicylaldehyde (2.79 mL, 35.9 mmol) and p-toluenesulfonic acid (20 mg, 0.1 mmol) in toluene (180 mL) was heated to reflux in a Dean-Stark apparatus for 2 h. After adding some triethylamine the reaction mixture was evaporated resulting in crude compound 2-[(2,6-dibromophenyl)iminomethyl]phenol (14 g, 100%).
後処理
- temperatureto reflux in a Dean-Stark apparatus for 2 h
- customwas evaporated
出典と根拠
- ORDレコード
- ord-857dd79300e54728be55fb33ddab7c0b
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07737136B2
反応ノート
読み込み中…