Phthalimide → 2-Amino-5-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3,6-dicarboxylic acid di-tert-butyl ester
反応式
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9]([NH2:26])[s:10][c:11]2[c:16]1[CH2:15][CH:14]([CH2:17][OH:18])[N:13]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:12]2.[O:27]=[C:28]1[NH:29][C:30](=[O:31])[c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]21.[O:57]=[C:58]([O:59][CH2:60][CH3:61])[N:62]=[N:63][C:64]([O:65][CH2:66][CH3:67])=[O:68].[O:69]1[CH2:70][CH2:71][CH2:72][CH2:73]1.[c:38]1([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9]([NH2:26])[s:10][c:11]2[c:16]1[CH2:15][CH:14]([CH2:17][N:29]1[C:28](=[O:27])[c:37]3[c:32]([cH:33][cH:34][cH:35][cH:36]3)[C:30]1=[O:31])[N:13]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:12]2
