Trifluoroacetic acid → HCID 58574251、化合物
反応式
[Cl:1][CH2:2][C:3]([NH:5][CH2:6][C:7]1([CH3:19])[CH2:11][CH2:10][CH2:9][N:8]1C(OC(C)(C)C)=O)=[O:4].C(O)(C(F)(F)F)=O>C(Cl)Cl>[Cl:1][CH2:2][C:3]([NH:5][CH2:6][C:7]1([CH3:19])[CH2:11][CH2:10][CH2:9][NH:8]1)=[O:4]参加物
4
実験手順
A solution of tert-butyl 2-((2-chloroacetamido)methyl)-2-methylpyrrolidine-1-carboxylate (0.7 g, 4.8 mmol) and TFA (3 mL) in DCM was stirred at room temperature for about 3 h. Then the solution was concentrated to give 300 mg of the crude product, which was directly used for the next step. MS (ESI): 191, 193 (MH+).
後処理
- concentrationThen the solution was concentrated
出典と根拠
- ORDレコード
- ord-d5fb570cca26452f99e9ecac9abc4429
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08772301B2
反応ノート
読み込み中…