((4-Methoxyphenyl)methyl)hydrazine → 3-(4-Methoxy-benzyl)-3,4-diaza-bicyclo[4.1.0]heptan-2,5-dione
反応式
[CH:1]12[C:7](=[O:8])[O:6][C:4](=O)[CH:2]1[CH2:3]2.[CH3:9][O:10][C:11]1[CH:19]=[CH:18][C:14]([CH2:15][NH:16][NH2:17])=[CH:13][CH:12]=1>C(#N)C>[CH3:9][O:10][C:11]1[CH:19]=[CH:18][C:14]([CH2:15][N:16]2[NH:17][C:4](=[O:6])[CH:2]3[CH:1]([CH2:3]3)[C:7]2=[O:8])=[CH:13][CH:12]=1参加物
4
実験手順
1.0 g (8.92 mmol) 1,2-cyclopropanedicarboxylic acid anhydride is dissolved in 5 ml acetonitrile, 1.5 g (9.86 mmol) 4-methoxy-benzyl-hydrazine dissolved in 5 ml acetonitrile are added dropwise and the mixture is refluxed overnight. During cooling to RT a precipitate is formed, which is filtered off, washed with acetonitrile and dried in the vacuum dryer at 50° C.
後処理
- additionare added dropwise
- temperaturethe mixture is refluxed overnight
- customis formed
- filtrationwhich is filtered off
- washwashed with acetonitrile
- customdried in the vacuum dryer at 50° C.
出典と根拠
- ORDレコード
- ord-579cbca122da45d592157a85c31868ed
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08772323B2
反応ノート
読み込み中…