HCID 68613896、化合物 → 2-Methoxy-7-quinolinamine
反応式
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][C:7]([N+:13]([O-])=O)=[CH:8][CH:9]=2)[N:4]=1>[Pd].CO>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][C:7]([NH2:13])=[CH:8][CH:9]=2)[N:4]=1参加物
4
実験手順
A methanol (10 ml) solution containing 2-methoxy-7-nitroquinoline (33 mg) obtained in the 1st step was prepared and subjected to a hydrogenation reaction (60° C.; 50 bar; flow rate: 1 ml/min; 10% Pd/C) using H-cube™. Then, the solvent was distilled away under reduced pressure, and a purple solid of 2-methoxyquinolin-7-amine (28 mg) was thus obtained.
後処理
- customobtained in the 1st step
- customwas prepared
- distillationThen, the solvent was distilled away under reduced pressure
出典と根拠
- ORDレコード
- ord-908a47b3dcb84914959a8df31eff6253
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08772320B2
反応ノート
読み込み中…