Benzoic acid, 4-ethyl-2-methyl-, methyl ester → 4-Ethyl-2-methylbenzoic acid

HRID 1625563ノート

反応式

HRID 1625563 の反応式
[CH2:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9]C)=[O:8])=[C:5]([CH3:13])[CH:4]=1)[CH3:2]>[OH-].[Na+]>[CH2:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([OH:9])=[O:8])=[C:5]([CH3:13])[CH:4]=1)[CH3:2]

参加物

3

反応物 1

HCID 10773666Benzoic acid, 4-ethyl-2-methyl-, methyl ester

生成物 1

HCID 105350174-Ethyl-2-methylbenzoic acid

試薬・触媒・溶媒 1

HCID 14798Sodium Hydroxide溶媒

反応条件

温度
60 °C

実験手順

Methyl 4-ethyl-2-methylbenzoate (example 10c) (2.37 g) was dissolved in aq. NaOH (1M, 40 mL) and the solution heated at 60° C. overnight. The mixture was washed with hexanes and the aqueous layer was acidified with 6N HCl to pH 2. The title product was obtained as a white precipitate, following filtration and drying (2.17 g, 80%).

後処理

  1. washThe mixture was washed with hexanes

出典と根拠

ORDレコード
ord-2ac80a917aef4e139b40125ed42d0830
出典データセット
uspto-grants-2014_07
特許番号
US08784782B2

反応ノート

読み込み中…