Iodine → HCID 86666998、化合物
反応式
[Cl:1][C:2]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[S:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[I:16]I>C(Cl)(Cl)Cl>[I-:16].[Cl:1][C:2]1[C:15]2[C:6](=[S+:7][C:8]3[C:13]([N:14]=2)=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1参加物
4
反応条件
- 温度
- 5 °C
実験手順
1-Chlorophenothiazine (664 mg, 2.84 mmol) was dissolved in CHCl3 (50 mL) and cooled to 5° C. The solution was stirred as a solution of I2 (2.16 g, 8.51 mmol) dissolved in CHCl3 (10 mL) was added dropwise. The mixture was stirred at 5° C. overnight and allowed to warm to RT. The solvent was evaporated to dryness. The residue was stirred in Et2O and was filtered off and washed with Et2O until the filtrate was colorless. The dark solid was dried under vacuum and used without purification.
後処理
- additionwas added dropwise
- temperatureto warm to RT
- customThe solvent was evaporated to dryness
- stirringThe residue was stirred in Et2O
- filtrationwas filtered off
- washwashed with Et2O until the filtrate
- customThe dark solid was dried under vacuum
- customused without purification
出典と根拠
- ORDレコード
- ord-7f0bcd1bd2db43f7a62b9a21ad4fc290
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08785434B2
反応ノート
読み込み中…