HCID 178526599、化合物 → HCID 178507526、化合物
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:14]=[CH:13][NH:12][N:11]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O>CO.[Pd]>[NH:12]1[CH:13]=[CH:14][C:10]([C:6]2[CH:5]=[C:4]([NH2:1])[CH:9]=[CH:8][CH:7]=2)=[N:11]1参加物
4
実験手順
To a solution of 3-(3-nitrophenyl)-1H-pyrazole 12.A (490 mg, 2.59 mmol, available from Oakwood) in methanol (5 mL) was added 10% Pd on carbon by weight (100 mg). The air was evacuated from the reaction flask and was replaced with hydrogen. The resulting slurry was stirred overnight at room temperature. The reaction mixture was filtered, and the mother liquor condensed to afford 3-(1H-pyrazol-3-yl)benzenamine 12.B (397 mg, 96% yield).
後処理
- customThe air was evacuated from the reaction flask
- filtrationThe reaction mixture was filtered
- customthe mother liquor condensed
出典と根拠
- ORDレコード
- ord-ee33acae7f0a4ba39d4c687744b00a6d
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08785468B2
反応ノート
読み込み中…