Isobutyric Acid → 1-Methyl-4-nitrosopiperidin-4-yl isobutyrate

HRID 1630429

反応式

HRID 1630429 の反応式
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=[N:8][OH:9])[CH2:4][CH2:3]1.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.[Pb+4].[C:27]([OH:32])(=[O:31])[CH:28]([CH3:30])[CH3:29]>>[C:27]([O:32][C:5]1([N:8]=[O:9])[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]1)(=[O:31])[CH:28]([CH3:30])[CH3:29]

参加物

4

反応物 3

HCID 6590Isobutyric AcidHCID 3390531-Methylpiperidin-4-one oximeHCID 178418268HCID 178418268、化合物

生成物 1

HCID 579545081-Methyl-4-nitrosopiperidin-4-yl isobutyrate

実験手順

1-Methyl-4-nitrosopiperidin-4-yl isobutyrate was prepared from 1-methyl-piperidin-4-one oxime, lead tetraacetate and isobutyric acid using conditions of General Method 3. 1H NMR (400MHz, chloroform-d) δ 2.82-2.94 (2H, m), 2.65 (1H, sept, 7.0 Hz), 2.36 (3H, s), 2.23-2.35 (4H, m), 1.83-1.92 (2H, m), 1.28 (3H, s), 1.27 (3H, s).

出典と根拠

ORDレコード
ord-8c54031138534b43b856ac1bb27e080d
出典データセット
uspto-grants-2014_07
特許番号
US08791134B2

関連ノート

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