Carbamic acid, ethyl ester → Ethyl N-tert-butylcarbamate

HRID 1632599ノート

反応式

HRID 1632599 の反応式
[C:1](=[O:6])([O:3][CH2:4][CH3:5])[NH2:2].[CH2:7]=[C:8]([CH3:10])[CH3:9]>C(O)C>[C:8]([NH:2][C:1](=[O:6])[O:3][CH2:4][CH3:5])([CH3:10])([CH3:9])[CH3:7]

参加物

4

反応物 2

HCID 5641Carbamic acid, ethyl esterHCID 8255Isobutylene

生成物 1

HCID 4189386Ethyl N-tert-butylcarbamate収率 93.8%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
70 °C

実験手順

A stirred mixture of 89 g of ethyl carbamate, 5 g of ethanol, 10 g of ®LEWASORB AC-10 and 70 g of isobutene was heated to 70° C. in a stirred autoclave, and stirring was continued at this temperature for 4 hours. After the reaction was complete, the catalyst was separated off and the mixture was worked up by distillation. 136 g (93% of theory) of ethyl N-tert.-butylcarbamate of boiling point 70°-71° C./20 mbar were obtained. Gas chromatography showed that the crude product contained 0.2 percent by weight of diisobutene, but not diethyl carbonate was detected.

後処理

  1. customthe catalyst was separated off
  2. distillationthe mixture was worked up by distillation

出典と根拠

ORDレコード
ord-29e69c9f6b674a1aa57aa531a5aed22a
出典データセット
uspto-grants-1984_10
特許番号
US04476316

反応ノート

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