Thionyl Chloride → 4-(Chlorocarbonyl)phenyl hexanoate
反応式
[C:1]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13](O)=[O:14])=[CH:11][CH:10]=1)(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].S(Cl)([Cl:20])=O>C1(C)C=CC=CC=1>[C:1]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13]([Cl:20])=[O:14])=[CH:11][CH:10]=1)(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]参加物
4
実験手順
A mixture of 10 g of the resultant 4-hexanoyloxybenzoic acid, 8 g thionyl chloride and 100 ml toluene was stirred and externally heated to be refluxed for three hours. After distilling off the toluene from the mixture, the residue was distilled under reduced pressure to give 8.8 g 4-hexanoyloxybenzoic acid chloride in 82% yield based upon the amount of the 4-hexanoyloxybenzoic acid.
後処理
- temperatureexternally heated
- temperatureto be refluxed for three hours
- distillationAfter distilling off the toluene from the mixture
- distillationthe residue was distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-ccf83df1dfea44009fa0983dc7eb010d
- 出典データセット
- uspto-grants-1984_10
- 特許番号
- US04478741
反応ノート
読み込み中…