Ammonium Chloride → HCID 18679754、化合物
反応式
[CH3:1][N:2]([CH3:22])[S:3]([N:6]1[CH:10]=[C:9]([C:11](=[O:21])[C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-])=O)[CH:13]=2)[N:8]=[CH:7]1)(=[O:5])=[O:4].[NH4+].[Cl-]>O.C(O)C.[Fe]>[NH2:18][C:14]1[CH:13]=[C:12]([CH:17]=[CH:16][CH:15]=1)[C:11]([C:9]1[N:8]=[CH:7][N:6]([S:3]([N:2]([CH3:22])[CH3:1])(=[O:4])=[O:5])[CH:10]=1)=[O:21]参加物
6
実験手順
To a mixture of Example 55B (3.24 g, 10 mmol) and NH4Cl (540 mg, 10 mmol) in water (15 mL) and ethanol (35 mL) was added iron powder (3.92 g, 70 mmol) and the mixture was refluxed for 1 hour. The mixture was filtered, the solid was washed with THF, and the combined filtrate and washings were removed under vacuum to provide 3 g (˜100%) of the title compound.
後処理
- temperaturethe mixture was refluxed for 1 hour
- filtrationThe mixture was filtered
- washthe solid was washed with THF
- customthe combined filtrate and washings were removed under vacuum
出典と根拠
- ORDレコード
- ord-bf35df752b1e43ed8b59d1fbd33d4f23
- 出典データセット
- uspto-grants-2003_01
- 特許番号
- US06503935B1
反応ノート
読み込み中…