Chlorosulfonic acid → 4-(3-Methyl-2-oxo-1-imidazolidinyl)benzenesulfonyl chloride

HRID 1634825ノート

反応式

HRID 1634825 の反応式
[CH3:1][N:2]1[CH:6]=[CH:5][N:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]1=[O:13].[Cl:14][S:15](O)(=[O:17])=[O:16]>>[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][C:10]([S:15]([Cl:14])(=[O:17])=[O:16])=[CH:9][CH:8]=2)[C:3]1=[O:13]

参加物

3

反応物 2

HCID 24638Chlorosulfonic acidHCID 197983301,3-Dihydro-1-methyl-3-phenyl-2H-imidazol-2-one

生成物 1

HCID 186784164-(3-Methyl-2-oxo-1-imidazolidinyl)benzenesulfonyl chloride

実験手順

A solution of 1-methyl-3-phenylimidazol-2-one (5.7 g, 32.3 mmol) in 10 mL of chlorosulfonic acid was stirred at ambient temperature for 30 minutes. The reaction mixture was poured into ice/water and extracted with ethyl acetate. The organic phase was separated, dried (Na2SO4) and concentrated in vacuo to a white solid (7.4 g). Used as is in the following prep.

後処理

  1. extractionextracted with ethyl acetate
  2. customThe organic phase was separated
  3. dry with materialdried (Na2SO4)
  4. concentrationconcentrated in vacuo to a white solid (7.4 g)

出典と根拠

ORDレコード
ord-f32be6f8ac794ae786cde1bc3dc3445f
出典データセット
uspto-grants-2003_01
特許番号
US06506901B2

反応ノート

読み込み中…