Benzoyl Peroxide → HCID 18675872、化合物

HRID 1635088ノート

反応式

HRID 1635088 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH3:8])[C:3]=1[O:9][CH3:10].[Br:11]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH2:8][Br:11])[C:3]=1[O:9][CH3:10]

参加物

5

反応物 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 105830464-Chloro-3-methoxy-2-methylpyridine

生成物 1

HCID 18675872HCID 18675872、化合物

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

4-Chloro-3-methoxy-2-methyl-pyridine (6.12 g) is dissolved in carbon tetrachloride (80 ml) then N-bromo-succinimide (7.12 g) and benzoyl peroxide (1 g) are added. The reaction mixture is refluxed under UV irradiation for 1.5 hour. The solid is filtered after cooling and the solvent evaporated. The desired product is purified by chromatography on silica gel.

後処理

  1. temperatureThe reaction mixture is refluxed under UV irradiation for 1.5 hour
  2. filtrationThe solid is filtered
  3. temperatureafter cooling
  4. customthe solvent evaporated
  5. customThe desired product is purified by chromatography on silica gel

出典と根拠

ORDレコード
ord-6591c0c517204113a4c93daf9a5f06cb
出典データセット
uspto-grants-2003_01
特許番号
US06509349B1

反応ノート

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