Benzonitrile, 4-bromo- → (4'-Cyano-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

HRID 1635160ノート

反応式

HRID 1635160 の反応式
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].B1(B2OC(C)(C)C(C)(C)O2)OC(C)(C)C(C)(C)O1.Br[C:38]1[CH:45]=[CH:44][C:41]([C:42]#[N:43])=[CH:40][CH:39]=1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:38]2[CH:45]=[CH:44][C:41]([C:42]#[N:43])=[CH:40][CH:39]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

参加物

4

反応物 3

HCID 12162Benzonitrile, 4-bromo-HCID 2733548Bis(pinacolato)diboraneHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

生成物 1

HCID 69592863(4'-Cyano-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

実験手順

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1), bis(pinacolato)diboron and 4-bromobenzonitrile according to the general procedure C. Obtained as a yellow solid (1.38 g).

出典と根拠

ORDレコード
ord-a1496142011f4bf1adf78c3e9784ea04
出典データセット
uspto-grants-2003_01
特許番号
US06509328B1

反応ノート

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