Oxalyl chloride → HCID 22605448、化合物
反応式
[CH3:1][C:2]1[CH:6]=[CH:5][N:4]([C:7]2[CH:15]=[CH:14][C:10]([C:11](O)=[O:12])=[CH:9][CH:8]=2)[N:3]=1.C(Cl)(=O)C([Cl:19])=O>ClCCl.CN(C)C=O>[CH3:1][C:2]1[CH:6]=[CH:5][N:4]([C:7]2[CH:15]=[CH:14][C:10]([C:11]([Cl:19])=[O:12])=[CH:9][CH:8]=2)[N:3]=1参加物
5
実験手順
To a suspension of 4-(3-methylpyrazol-1-yl)benzoic acid (1.84 g) in dichloromethane (25 ml) was added oxalyl chloride (1.16 g) and one drop of dimethylformamide. The mixture was stirred at room temperature for 18 hours and the volatile material was removed under reduced pressure. Dichloromethane was added, the solution filtered, and the solvent evaporated under reduced pressure to yield 4-(3-methylpyrazol-1-yl)benzoyl chloride as a yellow oil (1.76 g), which was utilized without further purification.
後処理
- customthe volatile material was removed under reduced pressure
- additionDichloromethane was added
- filtrationthe solution filtered
- customthe solvent evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-ede1adb01eb54cfe948923385d26ae60
- 出典データセット
- uspto-grants-2003_01
- 特許番号
- US06511974B1
反応ノート
読み込み中…