Acetone → 56540-58-0

HRID 1636407ノート

反応式

HRID 1636407 の反応式
[C:1]1([CH3:11])[CH:6]=[CH:5][C:4]([S:7](O)(=O)=O)=[CH:3][CH:2]=1.O.C(OCC)(=[O:15])C.[CH3:19][C:20]([CH3:22])=O>>[CH3:22][C:20]1[S:7][C:4]2[CH:3]=[CH:2][C:1]([CH:11]=[O:15])=[CH:6][C:5]=2[CH:19]=1

参加物

5

反応物 4

HCID 180AcetoneHCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 8857Ethyl Acetate

生成物 1

HCID 1435868256540-58-0

実験手順

A catalytic amount of p-toluenesulfonic acid is added to a solution of 1.5 g of 2-methyl-5-(1,3-dioxoran-2-yl)benzo[b]thiophene in 20 ml of acetone at room temperature, at which temperature the resulting mixture is stirred for 30 minutes. After the reaction, the solvent is removed from the reaction mixture by distillation under reduced pressure. The residue obtained are added 20 ml of water and 20 ml of ethyl acetate, after which the resulting organic layer is separated, washed successively with water and a saturated saline solution and then dried over anhydrous magnesium sulfate. The solvent is thereafter removed from the thus dried layer by distillation under reduced pressure, to obtain 1.15 g of colorless, solid 2-methylbenzo[b]thiophene-5-carbaldehyde.

後処理

  1. customAfter the reaction
  2. customthe solvent is removed from the reaction mixture by distillation under reduced pressure
  3. customThe residue obtained
  4. customafter which the resulting organic layer is separated
  5. washwashed successively with water
  6. dry with materiala saturated saline solution and then dried over anhydrous magnesium sulfate
  7. customThe solvent is thereafter removed from the thus dried layer by distillation under reduced pressure

出典と根拠

ORDレコード
ord-ba5b4cc5b191460e8218f34c9945c592
出典データセット
uspto-grants-2000_03
特許番号
US06034119

反応ノート

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