Oxalyl chloride → 3-Methylazulene-1-carbonyl chloride

HRID 1638975ノート

反応式

HRID 1638975 の反応式
[CH3:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=O)[C:5]2[C:11]=1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2.C(C1N2C(C=CC=C2)=C(C(OCC)=O)C=1)(=O)C.C(Cl)(=O)C([Cl:35])=O>ClCCl>[CH3:1][C:2]1[CH:3]=[C:4]([C:12]([Cl:35])=[O:14])[C:5]2[C:11]=1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2

参加物

5

反応物 3

HCID 65578Oxalyl chlorideHCID 838368ethyl 3-acetylindolizine-1-carboxylateHCID 13924938HCID 13924938、化合物

生成物 1

HCID 198402083-Methylazulene-1-carbonyl chloride

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

3-Methyl azulene-1-carbonyl chloride was prepared in situ from 3-methyl azulene-1-carboxylic acid (R. N. McDonald et al., J. Org. Chem., 41, 1822 [1976] by addition of one equivalent of oxalyl chloride to a solution of the acid in dichloromethane.

出典と根拠

ORDレコード
ord-1bfd657780484f339f55c349c4eee1e3
出典データセット
uspto-grants-1989_11
特許番号
US04882327

反応ノート

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