3-Phenylprop-2-enoyl chloride → HCID 3760131、化合物
反応式
[C:1]([O:5][CH3:6])(=[O:4])[NH:2][NH2:3].[C:7](Cl)(=[O:16])[CH:8]=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C(#N)C>[C:10]1([CH:9]=[CH:8][C:7]([NH:3][NH:2][C:1]([O:5][CH3:6])=[O:4])=[O:16])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1参加物
4
実験手順
To a solution of 27 g (0.3 moles) of methyl carbazate and 250 ml. of acetonitrile a solution of 50 g. (0.3 moles) of cinnamic chloride and 100 ml. of acetonitrile is added. The reaction mixture is heated to boiling for 15 hours. The mixture is cooled and the precipitated white crystals are filtered off. Thus 62.6 of the desired compound are obtained, yield 94.8%. M.p.: 165° C.
後処理
- temperatureThe reaction mixture is heated
- temperatureThe mixture is cooled
- filtrationthe precipitated white crystals are filtered off
出典と根拠
- ORDレコード
- ord-88d91b7900f745dbabe4a17912a30406
- 出典データセット
- uspto-grants-1989_11
- 特許番号
- US04883907
反応ノート
読み込み中…