Methyl 2-[(4-nitronaphthalen-1-yl)oxy]acetate → Methyl 2-((4-aminonaphthalen-1-yl)oxy)acetate
反応式
[CH3:1][O:2][C:3](=[O:19])[CH2:4][O:5][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([N+:16]([O-])=O)=[CH:8][CH:7]=1.[H][H]>CO.[Pd]>[CH3:1][O:2][C:3](=[O:19])[CH2:4][O:5][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([NH2:16])=[CH:8][CH:7]=1参加物
5
実験手順
(4-Nitro-naphthalen-1-yloxy)-acetic acid methyl ester (0.90 g) and 10% Pd/C (90 mg) in MeOH (150 ml) is stirred at room temperature under 1 atmosphere of hydrogen for 4 h. The mixture is then filtered through Celite® and evaporated to dryness to provide (4-amino-naphthalen-1-yloxy)-acetic acid methyl ester (0.72 g). MS 232 (M+1).
後処理
- filtrationThe mixture is then filtered through Celite®
- customevaporated to dryness
出典と根拠
- ORDレコード
- ord-27c2f7c47ab6475fa6347c96e2aed3a9
- 出典データセット
- uspto-grants-2012_02
- 特許番号
- US08114873B2
反応ノート
読み込み中…