Ibudilast → 2-Isopropylpyrazolo[1,5-a]pyridine

反応式

[CH3:1][CH:2]([C:4]1[C:12]([C:13]([CH:15]([NH2:17])[CH3:16])=[O:14])=[C:11]2[N:6]([CH:7]=[CH:8][CH:9]=[CH:10]2)[N:5]=1)[CH3:3].[CH3:18][CH:19]([C:21]1[C:22]([C:30](C(C)C)=[O:31])=[C:23]2[N:28]([N:29]=1)[CH:27]=[CH:26][CH:25]=[CH:24]2)[CH3:20].C(C1C=C2C=CC=CN2N=1)(C)C.CC(C)C=[O:50]>>[CH3:3][CH:2]([C:4]1[C:12]([C:13]([CH:15]([NH2:17])[CH3:16])=[O:14])=[C:11]2[N:6]([CH:7]=[CH:8][CH:9]=[CH:10]2)[N:5]=1)[CH3:1].[CH:19]([C:21]1[CH:22]=[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][N:28]2[N:29]=1)([CH3:20])[CH3:18].[CH:19]([C:21]1[C:22]([C:30]([OH:31])=[O:50])=[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][N:28]2[N:29]=1)([CH3:18])[CH3:20]