Ethanolamine → HCID 14209234、化合物

HRID 1646852ノート

反応式

HRID 1646852 の反応式
[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1Cl)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH2:13]([CH2:15][NH2:16])[OH:14]>O>[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1[NH:16][CH2:15][CH2:13][OH:14])=[CH:9][CH:8]=[CH:7][CH:6]=2

参加物

4

反応物 2

HCID 700EthanolamineHCID 6183063-Bromo-4-chloroquinoline

生成物 1

HCID 14209234HCID 14209234、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
150 °C

実験手順

A mixture of 9.1 g of 3-bromo-4-chloro-quinoline and 2.0 g of ethanolamine was heated at 150° C. for 30 minutes. The reaction mixture was cooled, 60 ml of water was added and the precipitate was collected by filtration and recrystallized from isopropanol. The yield was 9.5 g, mp 163°-165° C.

後処理

  1. temperatureThe reaction mixture was cooled
  2. filtrationthe precipitate was collected by filtration
  3. customrecrystallized from isopropanol

出典と根拠

ORDレコード
ord-2409ecd8fd9f41c08c040ff187eb3d5f
出典データセット
uspto-grants-1993_01
特許番号
US05182275

反応ノート

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