N,N-diethyl-2-nitrobenzenesulfonamide → 2-Amino-N,N-diethylbenzenesulfonamide
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10]([N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])(=[O:12])=[O:11])([O-])=O.[H][H]>[Pd].C(OCC)(=O)C>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10]([N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])(=[O:12])=[O:11]参加物
5
実験手順
In a pressure vessel a mixture of 133 g of o-nitro-N,N-diethylbenzenesulfonamide, 5 g of 10% palladium on carbon, and 500 ml of ethyl acetate was taken at 130° under 500 psi hydrogen pressure until hydrogen was no longer absorbed. The reaction mixture was cooled and the catalyst filtered off. Evaporation of the solvent in-vacuo gave 123 g of o-amino-N,N-diethylbenzenesulfonamide as a viscous oil which slowly crystallized to a solid, m.p. 45°-51°.
後処理
- customwas no longer absorbed
- temperatureThe reaction mixture was cooled
- filtrationthe catalyst filtered off
- customEvaporation of the solvent in-vacuo
出典と根拠
- ORDレコード
- ord-be77efdf7ffc452a9b641ae47ee8ab09
- 出典データセット
- uspto-grants-1983_11
- 特許番号
- US04417917
反応ノート
読み込み中…