Sodium Hydroxide → HCID 14304543、化合物

HRID 1649958ノート

反応式

HRID 1649958 の反応式
[CH3:1][O:2][C:3]1[CH:23]=[CH:22][C:6]([C:7]([C:9]2[CH:20]=[CH:19][C:12]([O:13][CH2:14][C:15]([O:17]C)=[O:16])=[C:11]([CH3:21])[CH:10]=2)=[O:8])=[CH:5][CH:4]=1.[OH-].[Na+]>O1CCOCC1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([C:9]2[CH:20]=[CH:19][C:12]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[C:11]([CH3:21])[CH:10]=2)=[O:8])=[CH:22][CH:23]=1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 13966816Methyl [4-(4-methoxybenzoyl)-2-methylphenoxy]acetate

生成物 1

HCID 14304543HCID 14304543、化合物

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

35.8 g of methyl 4-(4-methoxybenzoyl)-2-methylphenoxyacetate are stirred with a mixture of 240 ml of dioxane and 240 ml of 0.5N NaOH at room temperature. After the reaction is complete, the organic solvent is removed in vacuo, and the aqueous phase is adjusted to pH 3 with 2N HCl and extracted with ethyl acetate. The organic phase is washed with water, dried over magnesium sulfate and concentrated. Pale yellow crystals remain.

後処理

  1. customthe organic solvent is removed in vacuo
  2. extractionextracted with ethyl acetate
  3. washThe organic phase is washed with water
  4. dry with materialdried over magnesium sulfate
  5. concentrationconcentrated

出典と根拠

ORDレコード
ord-88813c6be48e4e3dbf0f8effcfe2495e
出典データセット
uspto-grants-1990_05
特許番号
US04922015

反応ノート

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