Trifluoroiodoethylene → 4-[4-(4-Propylcyclohexyl)cyclohexyl]-1-(1,2,2-trifluorovinyl)benzene

HRID 1653611

反応式

HRID 1653611 の反応式
[F:1][C:2]([F:6])=[C:3]([F:5])I.I[C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][CH:17]([CH:20]3[CH2:25][CH2:24][CH:23]([CH2:26][CH2:27][CH3:28])[CH2:22][CH2:21]3)[CH2:16][CH2:15]2)=[CH:10][CH:9]=1>[Zn].C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C1COCC1>[CH2:26]([CH:23]1[CH2:22][CH2:21][CH:20]([CH:17]2[CH2:18][CH2:19][CH:14]([C:11]3[CH:12]=[CH:13][C:8]([C:3]([F:5])=[C:2]([F:6])[F:1])=[CH:9][CH:10]=3)[CH2:15][CH2:16]2)[CH2:25][CH2:24]1)[CH2:27][CH3:28]

参加物

6

反応物 2

HCID 67755TrifluoroiodoethyleneHCID 13931028(trans,trans)-4-(4-Iodophenyl)-4'-propyl-1,1'-bi(cyclohexane)

生成物 1

HCID 200802044-[4-(4-Propylcyclohexyl)cyclohexyl]-1-(1,2,2-trifluorovinyl)benzene

試薬・触媒・溶媒 3

HCID 23994Zinc触媒HCID 178418397HCID 178418397、化合物触媒HCID 8028Tetrahydrofuran溶媒

実験手順

A mixture of 5.0 g (77 mmol) of zinc powder, 50 ml of THF and 13.5 g (65 mmol) of trifluoroiodoethylene is stirred overnight, initially with ice cooling, later at room temperature. 20.5 g (50 mmol) of 1-iodo-4-[4-(4-propylcyclohexyl)cyclohexyl]benzene and 1.1 g-of tetrakis(triphenylphosphine)palladium are then added.

出典と根拠

ORDレコード
ord-9e3c7aec233d464aa7cfacce147fef7c
出典データセット
uspto-grants-1995_04
特許番号
US05403512

関連ノート

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