Trifluoroacetic acid → (E)-N-(4-(4-(Ethyl(6-fluoro-6-methylheptyl)amino)-1-butenyl)phenyl)methanesulfonamide

HRID 1654304ノート

反応式

HRID 1654304 の反応式
[CH2:1]([N:3]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]([F:28])([CH3:27])[CH3:26])[CH2:4][CH2:5][CH2:6][CH:7]([C:9]1[CH:14]=[CH:13][C:12]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])=[CH:11][CH:10]=1)O)[CH3:2].FC(F)(F)C(O)=O>>[CH2:1]([N:3]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]([F:28])([CH3:27])[CH3:26])[CH2:4][CH2:5]/[CH:6]=[CH:7]/[C:9]1[CH:14]=[CH:13][C:12]([NH:15][S:16]([CH3:19])(=[O:17])=[O:18])=[CH:11][CH:10]=1)[CH3:2]

参加物

3

反応物 2

HCID 6422Trifluoroacetic acidHCID 9823219N-(4-(4-(Ethyl(6-fluoro-6-methylheptyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide

生成物 1

HCID 20080101(E)-N-(4-(4-(Ethyl(6-fluoro-6-methylheptyl)amino)-1-butenyl)phenyl)methanesulfonamide

実験手順

In the process as described in Example 2 the product from Example 17 is treated with trifluoroacetic acid to give the titled compound.

出典と根拠

ORDレコード
ord-b4000aba498f41a988c72506bc0df69c
出典データセット
uspto-grants-1995_04
特許番号
US05405997

反応ノート

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