Thionyl Chloride → 1-(Chloromethyl)pyrene

HRID 1654610

反応式

HRID 1654610 の反応式
S(Cl)([Cl:3])=O.O[CH2:6][C:7]1[C:20]2[C:21]3=[C:22]4[C:17](=[CH:18][CH:19]=2)[CH:16]=[CH:15][CH:14]=[C:13]4[CH:12]=[CH:11][C:10]3=[CH:9][CH:8]=1>C1C=CC=CC=1>[Cl:3][CH2:6][C:7]1[C:20]2[C:21]3=[C:22]4[C:17](=[CH:18][CH:19]=2)[CH:16]=[CH:15][CH:14]=[C:13]4[CH:12]=[CH:11][C:10]3=[CH:9][CH:8]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 1049771-Pyrenemethanol

生成物 1

HCID 975811-(Chloromethyl)pyrene

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

Thionyl chloride (15 mL, 200 mmol) was added dropwise to a suspension of 1-hydroxymethylpyrene (9.3 g, 40 mmol) in dry benzene (150 mL) at 0° C. and the mixture was stirred at room temperature overnight. Evaporation of the solvent under reduced pressure gave a creamy-white solid, m.p. 146°-148° C., yield: 9.6 g, 96%.

後処理

  1. customEvaporation of the solvent under reduced pressure
  2. customgave a creamy-white solid, m.p. 146°-148° C., yield: 9.6 g, 96%

出典と根拠

ORDレコード
ord-5fa99d94945c47728d395a4eec64461b
出典データセット
uspto-grants-1995_04
特許番号
US05409666

関連ノート

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