Sodium Iodide → HCID 54271327、化合物

HRID 1655994ノート

反応式

HRID 1655994 の反応式
[CH3:1][Si:2]([CH3:13])([CH2:9][CH2:10][CH2:11]Cl)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[I-:14].[Na+]>CC(C)=O>[CH3:1][Si:2]([CH3:13])([CH2:9][CH2:10][CH2:11][I:14])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

参加物

4

反応物 2

HCID 5238Sodium IodideHCID 12446004(3-Chloropropyl)(dimethyl)phenylsilane

生成物 1

HCID 54271327HCID 54271327、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Dimethyl(3-chloropropyl)phenylsilane [J. W. Wilt, W. K. Chwang, C. F. Dockus and N. M. Tomiuk, J. Am. Chem. Soc., 100, 5534, (1978)] (9 g, 48.8 mmol) and sodium iodide (29.5 g, 195 mmol) are refluxed in acetone during 24 hours. The mixture is filtered and the solvent is evaporated under reduced pressure. The residue is dissolved in diethyl ether and washed with water. The organic layer is dried with sodium sulfate, filtered and concentrated under reduced pressure to afford pure dimethyl(3-iodopropyl)phenylsilane as a slightly yellow oil (12.5 g, 93%).

後処理

  1. filtrationThe mixture is filtered
  2. customthe solvent is evaporated under reduced pressure
  3. dissolutionThe residue is dissolved in diethyl ether
  4. washwashed with water
  5. dry with materialThe organic layer is dried with sodium sulfate
  6. filtrationfiltered
  7. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-f6db99b6098344adb2f9018a0b2b87ff
出典データセット
uspto-grants-1993_10
特許番号
US05252587

反応ノート

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