Methanol → HCID 53872663、化合物
反応式
[Na].CO[CH:4]([CH3:7])[C:5]#[N:6].[CH3:8][O:9][C:10]1[CH:11]=[C:12]([CH:15]=[C:16]2[O:20][CH2:19][O:18][C:17]=12)[CH:13]=O.[CH3:21][OH:22]>>[CH3:8][O:9][C:10]1[CH:11]=[C:12]([CH:15]=[C:16]2[O:20][CH2:19][O:18][C:17]=12)[CH:13]=[C:4]([CH2:7][O:22][CH3:21])[C:5]#[N:6]参加物
5
実験手順
3.8 g. of sodium were dissolved in 120 ml. of methanol under reflux. 56 g. of methoxypropionitrile and 60 g. of 3-methoxy-4,5-methylenedioxybenzaldehyde were then added and refluxed in the methanol mixture for 5 hours. Upon chilling, 3-methoxy-4,5-methylenedioxy-α-methoxymethyl-cinnamonitrile crystallized in needles of m.p. = 115°, in a yield of 68 g. = 83 percent. A sample of analysis was recrystallized from methanol, m.p. 115.5°-116.5°.
後処理
- temperatureUpon chilling
- custom3-methoxy-4,5-methylenedioxy-α-methoxymethyl-cinnamonitrile crystallized in needles of m.p. = 115°, in a yield of 68 g
- customA sample of analysis was recrystallized from methanol, m.p. 115.5°-116.5°
出典と根拠
- ORDレコード
- ord-7d46f5eb344942c394e504ee91dd2aa3
- 出典データセット
- uspto-grants-1976_06
- 特許番号
- US03962435
反応ノート
読み込み中…