1-Bromo-3-chloropropane → 2,3,6,7-Tetrahydro-5H-[1,3]thiazolo[2,3-b][1,3]thiazin-4-ium bromide

HRID 1658046ノート

反応式

HRID 1658046 の反応式
[S:1]1[CH2:5][CH2:4][NH:3][C:2]1=[S:6].[Br:7][CH2:8][CH2:9][CH2:10]Cl>C(#N)C>[Br-:7].[S:1]1[C:2]2[S:6][CH2:8][CH2:9][CH2:10][N+:3]=2[CH2:4][CH2:5]1

参加物

4

反応物 2

HCID 80061-Bromo-3-chloropropaneHCID 27236992-Thiazolidinethione

生成物 1

HCID 214290162,3,6,7-Tetrahydro-5H-[1,3]thiazolo[2,3-b][1,3]thiazin-4-ium bromide

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

A mixture of 12 g. of thiazolidine-2-thione, and 16 g. of 1-bromo-3-chloro propane in 100 ml. of acetonitrile is refluxed for 12 hours, cooled and the product removed by filtration. Recrystallization from ethanol gives 2,3,5,6-tetrahydrothiazolo[2,3-b]-(1,3)-thiazinium bromide.

後処理

  1. additionA mixture of 12 g
  2. temperaturecooled
  3. customthe product removed by filtration
  4. customRecrystallization from ethanol

出典と根拠

ORDレコード
ord-2c88d7ebca164b9290a79b7c323da0ed
出典データセット
uspto-grants-1976_06
特許番号
US03962437

反応ノート

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