Benzoyl Peroxide → HCID 12370782、化合物

HRID 1658145ノート

反応式

HRID 1658145 の反応式
[Br:1]N1C(=O)CCC1=O.[CH3:9][C:10]1[CH:24]=[CH:23][C:13]2[N:14]=[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[O:16][C:12]=2[CH:11]=1.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:1][CH2:9][C:10]1[CH:24]=[CH:23][C:13]2[N:14]=[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[O:16][C:12]=2[CH:11]=1

参加物

5

反応物 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 123707806-Methyl-2-phenyl-1,3-benzoxazole

生成物 1

HCID 12370782HCID 12370782、化合物

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

N-Bromosuccinimide (25.9 gm) was added to a cold solution of 6-methyl-2-phenylbenzoxazole (30 gm) in carbon tetrachloride (250 ml). Benzoyl peroxide (500 mg) was added and the mixture was heated under reflux for 3 hr. in the presence of u.v. light. The solid residue was filtered off. The filtrate was evaporated down slightly, treated with carbon and allowed to cool. The crystals which were formed were recrystallised from benzene to yield 6-bromomethyl-2-phenylbenzoxazole, m.p. 162°C.

後処理

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 3 hr
  3. filtrationThe solid residue was filtered off
  4. customThe filtrate was evaporated down slightly,
  5. additiontreated with carbon
  6. temperatureto cool
  7. customThe crystals which were formed
  8. customwere recrystallised from benzene

出典と根拠

ORDレコード
ord-b52987d3108045ed9fabb90b0a07b72a
出典データセット
uspto-grants-1976_06
特許番号
US03962452

反応ノート

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