Methyl chloroformate → Benzenesulfonamide, 4-(2,4-dioxo-3-phenyl-1-imidazolidinyl)-

反応式

[S:1]([C:5]1[CH:21]=[CH:20][C:8]([NH:9][CH2:10][C:11]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:12])=[CH:7][CH:6]=1)(=[O:4])(=[O:3])[NH2:2].Cl[C:23](OC)=[O:24]>>[S:1]([C:5]1[CH:6]=[CH:7][C:8]([N:9]2[CH2:10][C:11](=[O:12])[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:23]2=[O:24])=[CH:20][CH:21]=1)(=[O:3])(=[O:4])[NH2:2]

参加物

反応物 2

HCID 6586Methyl chloroformate

HCID 21528871HCID 21528871、化合物

生成物 1

HCID 3041018Benzenesulfonamide, 4-(2,4-dioxo-3-phenyl-1-imidazolidinyl)-

実験手順

2-(4-Sulphamoylanilino)-N-phenylacetamide (1.5 g) and methyl chloroformate (15.0 ml) were heated together for 3 hours in an autoclave at 130°C. The product was filtered off as crystals; yield 500 mg, m.p. 255° - 257°C (acetone).

後処理

filtrationThe product was filtered off as crystals

出典と根拠

ORDレコード: ord-912cb6ca3e36496fa5178eb73dd1acfe
出典データセット: uspto-grants-1976_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03963706

反応ノート

読み込み中…